Anti-CD100(133-1C6)
CAT:
37-BNUB0932-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-CD100(133-1C6)
- Description: CD100 (also known as Semaphorin 4D), is a homodimeric protein comprised of 50 kDa subunits. It is expressed on resting T cells and weakly on other lymphocytes, and its expression is increased on B and T cells after stimulation. CD100 is a cell surface receptor that binds to CD72, Plexin B1 and Plexin B2. It promotes B cell aggregation, cell survival, and cell proliferation.
- Synonyms: CD100; Semaphorin-4D; SEMA4D
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: SEMA4D
- Gene ID: 10507
- NCBI Gene ID: 494406
- UniProt: Q92854
- Cellular Locus: Plasma membrane
- Host: Mouse
- Species Reactivity: Baboon, Human
- Immunogen: PHA stimulated human peripheral blood lymphocytes.
- Target Antigen: CD100 | Semaphorin-4D
- Clonality: Monoclonal
- Isotype: IgM κ
- Clone: 133-1C6
- Conjugation: Purified, with BSA
- Source: Animal
- Applications: Flow, surface (published) | Functional studies (published) | ELISA (published)
- Validated Applications: FC, ELISA
- Field of Research: Immunology, Neuroscience, Signal transduction
- Positive Control: Daudi, Raji, HUT-78, Kg1a, U937, and human lymphocytes. Human tonsils and lymph nodes.
- Concentration: 0.2 mg/mL
- Buffer: PBS, 0.05% BSA, 0.05% azide
- Molecular Weight: 50 kDa (Monomer)
- Additionnal Information: Immunofluorescence: 0.5-1 ug/mL|Does not react with horse, others not tested|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user
- References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Frontiers Immunol (2017) 8: 765. (functional studies) Frontiers Immunol (2021) 12:240. (ELISA) Paterson J., Ailles L.E. (2018) High Throughput Flow for Cell Surface Profiling. In: Hawley T., Hawley R. (eds) Flow Protocols. Methods in Molecular Biology, vol 1678. Humana Press, New York, NY. (Flow)
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years