CD10 (CB-CALLA), 0.2mg/mL

• Description :

  CD10 (also known as Common Acute Lymphocytic Leukemia Antigen (CALLA) ) is a type II transmembrane protein. It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML) . It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms :

  CD10; Neprilysin; Atriopeptidase; Common acute lymphocytic leukemia antigen (CALLA) ; Enkephalinase; gp100; Membrane metalloendopeptidase; Neutral endopeptidase

• UNSPSC :

  41116161

• UNSPSC Description :

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name :

  MME

• Gene ID :

  4311

• NCBI Gene ID :

  307734

• UniProt :

  P08473

• Swiss Prot :

  P08473

• Host :

  Mouse

• Species Reactivity :

  Human

• Reactivity :

  CD10

• Immunogen :

  Human CD10

• Target Antigen :

  CD10

• Clonality :

  Monoclonal

• Clone :

  CB-CALLA

• Type :

  Primary

• Source :

  Animal

• Origin :

  Animal

• Applications :

  Flow (verified) |Flow, surface (published) |IF (verified)

• Field of Research :

  Immunology, Proteases

• Positive Control :

  Tonsil, small intestine, kidney

• Stability :

  2 years

• Concentration :

  0.2 mg/mL

• Buffer :

  PBS, 0.05% BSA, 0.05% azide

• Molecular Weight :

  100 kDa

• References & Citations :

  Note: References for this clone sold by other suppliers may be listed for expected applications. Immunology (2011) 134: 419-433. (Flow, surface) Blood (2015) 125(20): 3144-3152. (Flow, surface)

• Shipping Conditions :

  RT (ND)

• Storage Conditions :

  Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life :

  Guaranteed for at least 24 months from date of receipt when stored as recommended

• Fragment :

  IgG1, kappa

• Species :

  Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

• Classification :

  PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

• CAS Number :

  9007-83-4

• Conjugate :

  Purified, with BSA