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KLK15 rabbit pAb

CAT: 0855-ES15278-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15278-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
UniProt
Q9H2R5
Swiss Prot
Q9H2R5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human KLK15 AA range: 20-100
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; WB
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, WB 1:500-2000
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Secreted .
Other Product Names
Kallikrein-15 (EC 3.4.21.-; ACO protease)
Gene ID (Human)
55554

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