Gemcitabine triphosphate (trisodium)

Gemcitabine triphosphate (trisodium)

• UNSPSC Description: Gemcitabine triphosphate (trisodium) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/gemcitabine-triphosphate-trisodium.html
• Solubility: H2O : 125 mg/mL (ultrasonic)
• Smiles: NC(C=CN1[C@H]2C(F)(F)[C@H](O)[C@@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)O2)=NC1=O
• Molecular Weight: 569.08
• References & Citations: [1]Shewach DS, et al. Gemcitabine and radiosensitization in human tumor cells. Invest New Drugs. 1996;14(3):257-63.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported