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Gemcitabine triphosphate

CAT: 0804-HY-17026ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-17026ASize:1 Each
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Description
Gemcitabine triphosphate (dFdCTP) is one of the two nucleoside metabolites of Gemcitabine in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells[1][2].
CAS Number
110988-86-8
Product Name Alternative
DFdCTP
UNSPSC
12352005
Target
Drug Metabolite; Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gemcitabine-triphosphate.html
Solubility
10 mM in DMSO
Smiles
NC(C=CN1[C@H]2C(F)(F)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)=NC1=O
Molecular Formula
C9H14F2N3O13P3
Molecular Weight
503.14
References & Citations
[1]Shewach DS, et al. Gemcitabine and radiosensitization in human tumor cells. Invest New Drugs. 1996;14 (3) :257-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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