DNA Polymerase lambda Recombinant Rabbit Monoclonal Antibody [PSH05-24]
CAT:
992-HA722253
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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DNA Polymerase lambda Recombinant Rabbit Monoclonal Antibody [PSH05-24]
- Description: DNA polymerase lambda, also known as Pol λ, is an enzyme found in all eukaryotes. In humans, it is encoded by the POLL gene. Pol λ is a member of the X family of DNA polymerases. It is thought to resynthesize missing nucleotides during non-homologous end joining (NHEJ), a pathway of DNA double-strand break (DSB) repair. NHEJ is the main pathway in higher eukaryotes for repair of DNA DSBs. Chromosomal DSBs are the most severe type of DNA damage. During NHEJ, duplexes generated by the alignment of broken DNA ends usually contain small gaps that need to be filled in by a DNA polymerase. DNA polymerase lambda can perform this function.
- Product Name Alternative: BETA N antibody BETAN antibody DNA directed DNA polymerase lambda antibody DNA polymerase beta 2 antibody DNA polymerase beta-2 antibody DNA polymerase kappa antibody DNA polymerase kappa DNA polymerase beta N antibody DNA polymerase lambda antibody DNA polymerase lamda2 antibody DPOLL_HUMAN antibody EC 2.7.7.7,EC 4.2.99. antibody FLJ46002 antibody OTTHUMP00000020321 antibody OTTHUMP00000020323 antibody OTTHUMP00000059179 antibody Pol beta2 antibody POL KAPPA antibody Pol Lambda antibody POLKAPPA antibody POLL antibody Polymerase DNA directed lambda antibody
- Abbreviation: POLL
- CAS Number: 9000-83-3
- Swiss Prot: Q9UGP5 Human, Q9QXE2 Mouse
- Cellular Locus: Nucleus, Chromosome.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Monkey
- Immunogen: Recombinant protein within human DNA Polymerase lambda aa 1-575 / 575.
- Isotype: IgG
- Clone: PSH05-24
- Conjugation: Non-conjugated
- Type: Recombinant Rabbit monoclonal Antibody
- Applications: WB, IHC-P
- Positive Control: HeLa cell lysate, A549 cell lysate, 293T cell lysate, HepG2 cell lysate, mouse testis tissue lysate, COS-1 cell lysate, human testis tissue.
- Concentration: 1 mg/mL
- Dilution: WB: 1:2,000 ;IHC-P: 1:1,000
- Purity: Protein A affinity purified.
- Form: Liquid
- Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 63 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: Yes