Morphine Tolerance Peptide

Morphine Tolerance Peptide Catalog number: MDP0434 CAS Number: 90954-53-3 Sequence: cyclo(Leu-Gly) Amount: 10 mg Molecular Weight: 170 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: -20 °C WARNING: For in vitro Research Use Only. NOT for use on humans or animals. Grade: Biotechnology grade. All products are highly pure. References: 1: Sorokina NS, Starostina MV. Myelopeptides Reduce Morphine Tolerance in C57BL/6j Mice Bull Exp Biol Med. 2021 Sep;171(5):623-626. 2: Liu DQ, Zhou YQ, Gao F. Targeting Cytokines for Morphine Tolerance: A Narrative Review Curr Neuropharmacol. 2019;17(4):366-376. 3: Blomqvist KJ, Viisanen H, Ahlström FHG, Jokinen V, Sidorova YA, Suleymanova I, Rauhala PV, Kalso EA, Lilius TO. Morphine-3-glucuronide causes antinociceptive cross-tolerance to morphine and increases spinal substance P expression Eur J Pharmacol. 2020 May 15;875:173021. 4: Gupta K, Vats ID, Gupta YK, Saleem K, Pasha S. Lack of tolerance and morphine-induced cross-tolerance to the analgesia of chimeric peptide of Met-enkephalin and FMRFa Peptides. 2008 Dec;29(12):2266-75. 5: Bell RL, Vaccarino AL, Olson RD, Olson GA, Nores WL, Cambre JG, Zadina JE, Kastin AJ. Tolerance and morphine-induced cross-tolerance are not shown to Tyr-W-MIF-1 analgesia Peptides. 1999;20(8):971-8. 6: Özdemir-Çezik S, Nurten A, Midilli B, Gürtekin B, Enginar N. Effect of oxytocin pretreatment on the development of morphine tolerance and dependence in rats Neurosci Lett. 2022 Jul 27;784:136764. 7: Powell KJ, Ma W, Sutak M, Doods H, Quirion R, Jhamandas K. Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists Br J Pharmacol. 2000 Nov;131(5):875-84. 8: Shen CH, Tsai RY, Wong CS. Role of neuroinflammation in morphine tolerance: effect of tumor necrosis factor-α Acta Anaesthesiol Taiwan. 2012 Dec;50(4):178-82. 9: Wang Z, Ma W, Chabot JG, Quirion R. Cell-type specific activation of p38 and ERK mediates calcitonin gene-related peptide involvement in tolerance to morphine-induced analgesia FASEB J. 2009 Aug;23(8):2576-86. 10: Gupta S, Pasha S, Gupta YK, Bhardwaj DK. Chimeric peptide of Met-enkephalin and FMRFa induces antinociception and attenuates development of tolerance to morphine antinociception Peptides. 1999;20(4):471-8.
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Catalog Number: MDP0434 (10 mg)

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