MCD-Peptide

• Description:

  MCD-Peptide Catalog number: MDP0634 CAS Number: 23025-68-5 Sequence: Ile-Lys-Cys-Asn-Cys-Lys-Arg-His-Val-Ile-Lys-Pro-His-Ile-Cys-Arg-Lys-Ile-Cys-Gly-Lys-Asn-NH2 (Disulfide bonds between Cys3-Cys15 and Cys5-Cys19) Amount: 500 ug Molecular Weight: 2587.2 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: -20 °C WARNING: For in vitro Research Use Only. NOT for use on humans or animals. Grade: Biotechnology grade. All products are highly pure. References: 1: Buku A. Mast cell degranulating (MCD) peptide: a prototypic peptide in allergy and inflammation Peptides. 1999;20(3):415-20. 2: Buku A, Condie BA, Price JA, Mezei M. [Ala12]MCD peptide: a lead peptide to inhibitors of immunoglobulin E binding to mast cell receptors J Pept Res. 2005 Sep;66(3):132-7. 3: Habermann E. Neurotoxicity of apamin and MCD peptide upon central application Naunyn Schmiedebergs Arch Pharmacol. 1977 Nov;300(2):189-91. 4: Fujimoto I, Ikenaka K, Kondo T, Aimoto S, Kuno M, Mikoshiba K. Mast cell degranulating (MCD) peptide and its optical isomer activate GTP binding protein in rat mast cells FEBS Lett. 1991 Aug 5;287(1-2):15-8. 5: El Mehdi I, Falcão SI, Boujraf S, Mustapha H, Campos MG, Vilas-Boas M. Analytical methods for honeybee venom characterization J Adv Pharm Technol Res. 2022 Jul-Sep;13(3):154-160. 6: Buku A, Reibman J, Pistelli A, Blandina P, Gazis D. Mast cell degranulating (MCD) peptide analogs with reduced ring structure J Protein Chem. 1992 Jun;11(3):275-80. 7: Bidard JN, Mourre C, Gandolfo G, Schweitz H, Widmann C, Gottesmann C, Lazdunski M. Analogies and differences in the mode of action and properties of binding sites (localization and mutual interactions) of two K+ channel toxins, MCD peptide and dendrotoxin I Brain Res. 1989 Aug 21;495(1):45-57. 8: Hanson JM, Morley J, Soria-Herrera C. Anti-inflammatory property of 401 (MCD-peptide), a peptide from the venom of the bee Apis mellifera (L.) Br J Pharmacol. 1974 Mar;50(3):383-92. 9: Jentsch J, Mücke HW. Bee venom peptides XVIII. Peptide-m and mcd-peptide: Isolation and characterization Int J Pept Protein Res. 1977 Jan;9(1):78-9. 10: Bidard JN, Gandolfo G, Mourre C, Gottesmann C, Lazdunski M. The brain response to the bee venom peptide MCD. Activation and desensitization of a hippocampal target Brain Res. 1987 Aug 25;418(2):235-44.
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• Short Description:

  Catalog Number: MDP0634 (500 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5