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PP1

CAT: 0804-HY-13804-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13804-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PP1 is a potent, and Src family-selective tyrosine kinase inhibitor with IC50 of 5 and 6 nM for Lck and Fyn, respectively.
CAS Number
172889-26-8
Product Name Alternative
AGL 1872; EI 275
UNSPSC
12352005
Hazard Statement
H301
Target
Apoptosis; Src
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PP1.html
Purity
99.57
Solubility
DMSO : 28 mg/mL (ultrasonic)
Smiles
NC1=C2C(N(C(C)(C)C)N=C2C3=CC=C(C)C=C3)=NC=N1
Molecular Formula
C16H19N5
Molecular Weight
281.36
Precautions
H301
References & Citations
[1]Hanke JH, et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J Biol Chem. 1996 Jan 12;271 (2) :695-701.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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