Coelenterazine (ALSO KNOWN AS NATIVE COE

Coelenterazine (ALSO KNOWN AS NATIVE COE

• Description: Coelenterazine (native form) is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. The aequorin complex has been used as an excellent calcium indicator that can measure a broad concentration range of calcium from ~0.1 uM to gt;100 uM. Renilla luciferase has been widely used as a reporter protein. Renilla luciferase/coelenterazine has also been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to study protein-protein interactions. Other uses of coelenterazine include chemiluminescent detection of superoxide anion and peroxynitrite in cells or tissues. Also see water soluble Aquaphile #x2122; Coelenterazine.
  • Yellow solid soluble in MeOH or EtOH
  • Store at -20 deg;C and protect from light
  • C₂₆H₂₁N₃O₃
  • MW: 423
  • [55779-48-1]
• CAS Number: 55779-48-1
• UNSPSC: 41116105
• UNSPSC Description: Chemistry reagents or solutions
• Source: Synthetic
• Storage Conditions: -35°C; Store with desiccant; Protect from light
• Shelf Life: 3 years