Ingenol

Ingenol

• CAS Number: 30220-46-3
• UNSPSC Description: Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.
• Target Antigen: PKC
• Type: Natural Products
• Related Pathways: Epigenetics;TGF-beta/Smad
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/Ingenol.html
• Purity: 99.51
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O[C@@]([C@@H](C(CO)=C[C@@]1([H])[C@H](C2(C)C)[C@H]2C3)O)([C@H]4O)[C@]([C@@H]3C)(C=C4C)C1=O
• Molecular Weight: 348.439
• References & Citations: [1]Hasler CM, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52(1):202-8.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched