Endoxifen (E-isomer hydrochloride)
CAT:
804-HY-18719C-03
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Endoxifen (E-isomer hydrochloride)
- CAS Number: 1197194-61-8
- UNSPSC Description: Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), an E-isomer of Endoxifen, is an impurity in Endoxifen Z-isomer agent substance. Endoxifen E-isomer hydrochloride exhibits antiestrogenic effects[1][2].
- Target Antigen: Estrogen Receptor/ERR
- Type: Reference compound
- Related Pathways: Vitamin D Related/Nuclear Receptor
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Endoxifen-E-isomer-hydrochloride.html
- Purity: 98.20
- Solubility: DMSO : ≥ 30 mg/mL
- Smiles: OC1=CC=C(/C(C2=CC=C(OCCNC)C=C2)=C(C3=CC=CC=C3)/CC)C=C1.[H]Cl
- Molecular Weight: 409.95
- References & Citations: [1]Elkins P, et, al. Characterization of the isomeric configuration and impurities of (Z)-endoxifen by 2D NMR, high resolution LC⬜MS, and quantitative HPLC analysis. J Pharm Biomed Anal. 2014 Jan;88:174-9.|[2]Zheng Y, et, al. Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metab Dispos. 2007 Oct;35(10):1942-8.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported