IDD-8E

• Description :

  IDD-8E is an effective anti-pseudomonal agent (MIC =4.4 μM) with no cytotoxicity. IDD-8E shows significant pseudomonal killing and disruption of pseudomonal biofilm. IDD-8E binds to the ATP-binding pocket of WaaP and also inhibits other ESKAPE pathogens. [1]

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/idd-8e.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C=C1)=CC2=C1N=C(NC3=NC(C4=CC(OC)=C(OC)N=C4)=CC(N3)=O)N=C2C

• Molecular Formula :

  C21H20N6O3

• Molecular Weight :

  404.42

• References & Citations :

  [1]Rakshit M et al. Uncovering the potentiality of quinazoline derivatives against Pseudomonas aeruginosa with antimicrobial synergy and SAR analysis. J Antibiot. 2024 MAR

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported