IDD-8E

• UNSPSC Description:

  IDD-8E is an effective anti-pseudomonal agent (MIC =4.4 μM ) with no cytotoxicity. IDD-8E shows significant pseudomonal killing and disruption of pseudomonal biofilm. IDD-8E binds to the ATP-binding pocket of WaaP and also inhibits other ESKAPE pathogens. [1]

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/idd-8e.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C=C1)=CC2=C1N=C(NC3=NC(C4=CC(OC)=C(OC)N=C4)=CC(N3)=O)N=C2C

• Molecular Weight:

  404.42

• References & Citations:

  [1]Rakshit M et al. Uncovering the potentiality of quinazoline derivatives against Pseudomonas aeruginosa with antimicrobial synergy and SAR analysis. J Antibiot. 2024 MAR

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported