Recombinant Human Alpha-1-Antitrypsin

Recombinant Human Alpha-1-Antitrypsin

• Description: Recombinant Human Alpha-1-Antitrypsin
• Product Name Alternative: A1AT
• CAS Number: 9000-83-3
• UniProt: P01009
• Reactivity: Human
• Target Antigen: Alpha-1-antitrypsin
• Target: Alpha-1-Antitrypsin
• Type: Protein
• Applications: WB
• Concentration: Lot Specific
• Dilution: Dilute in PBS or medium that is identical to that used in the assay system.
• Form: Liquid
• Buffer: 20 mM Tris
• Storage Conditions: Although stable at 4°C for 4 weeks, product is best stored at or below -20°C. For long-term storage, addition of a carrier protein (such as 0.1% HSA or BSA) is recommended. For in vitro investigational use only.
• Specificity: Alpha-1-Antitrypsin
• Formulation: Sterile-filtered colorless solution contains 20mM Tris-HCl, pH 7.5, 1mM DTT, 10% glycerol, and 2mM EDTA.
• Buffer pH: pH 7.5
• Target Background: Alpha-1-antitrypsin (A1AT) is a serine protease inhibitor that inhibits the catalytic domain of elastase, plasmin, collagenase, thrombin, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. Defects in the A1AT gene can lead to emphysema or liver disease. Increased levels of serum A1AT are found in cases of lung and prostate cancers and as an acute phase response to tissue necrosis and inflammation.