Human Recombinant Src

• Description:

  Human Recombinant Src _x000D_ Catalog number: B2016970_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 µg_x000D_ Molecular Weight or Concentration: 86 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: Proto-oncogene Tyrosine-protein Kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src, ,_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Liu H, Zhang H, Wu X, Ma D, Wu J, Wang L, Jiang Y, Fei Y, Zhu C, Tan R, Jungblut P, Pei G, Dorhoi A, Yan Q, Zhang F, Zheng R, Liu S, Liang H, Liu Z, Yang H, Chen J, Wang P, Tang T, Peng W, Hu Z, Xu Z, Huang X, Wang J, Li H, Zhou Y, Liu F, Yan D, Kaufmann SHE, Chen C, Mao Z, Ge B. Nuclear cGAS suppresses DNA repair and promotes tumorigenesis Nature. 2018 Nov;563(7729):131-136._x000D_ 2: Yang X, Xu R, Lin Y, Zhen Y, Wei J, Hu G, Sun H. Recombinant adenovirus of human p66Shc inhibits MCF-7 cell proliferation Sci Rep. 2016 Aug 17;6:31534._x000D_ 3: Chatzizacharias NA, Kouraklis GP, Giaginis CT, Theocharis SE. Clinical significance of Src expression and activity in human neoplasia Histol Histopathol. 2012 Jun;27(6):677-92._x000D_ 4: Fujishima H, Nakano S, Tatsumoto T, Masumoto N, Niho Y. Interferon-alpha and -gamma inhibit the growth and neoplastic potential of v-src-transformed human epithelial cells by reducing Src tyrosine kinase activity Int J Cancer. 1998 May 4;76(3):423-9._x000D_ 5: Bjorge JD, Bellagamba C, Cheng HC, Tanaka A, Wang JH, Fujita DJ. Characterization of two activated mutants of human pp60c-src that escape c-Src kinase regulation by distinct mechanisms J Biol Chem. 1995 Oct 13;270(41):24222-8._x000D_ 6: Bai KJ, Chen BC, Pai HC, Weng CM, Yu CC, Hsu MJ, Yu MC, Ma HP, Wu CH, Hong CY, Kuo ML, Lin CH. Thrombin-induced CCN2 expression in human lung fibroblasts requires the c-Src/JAK2/STAT3 pathway J Leukoc Biol. 2013 Jan;93(1):101-12._x000D_ 7: Bonham K, Ritchie SA, Dehm SM, Snyder K, Boyd FM. An alternative, human SRC promoter and its regulation by hepatic nuclear factor-1alpha J Biol Chem. 2000 Dec 1;275(48):37604-11._x000D_ 8: Takeichi M, Hirano S, Matsuyoshi N, Fujimori T. Cytoplasmic control of cadherin-mediated cell-cell adhesion Cold Spring Harb Symp Quant Biol. 1992;57:327-34._x000D_ 9: Holmes TC, Fadool DA, Ren R, Levitan IB. Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain Science. 1996 Dec 20;274(5295):2089-91._x000D_ 10: Ma XM, Shen ZH, Liu ZY, Wang F, Hai L, Gao LT, Wang HS. Heparanase promotes human gastric cancer cells migration and invasion by increasing Src and p38 phosphorylation expression Int J Clin Exp Pathol. 2014 Aug 15;7(9):5609-21. eCollection 2014._x000D_ _x000D_ Products Related to Human Recombinant Src can be found at Proteins

• Short Description:

  Catalog Number: B2016970 (1 µg)_x000D_ Human Recombinant Src is a high quality enzyme that plays a role in cell signaling and regulation of cell growth. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3