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GNE-0877

CAT: 0026-B2942-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2942-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNE-0877 is a selective, brain-penetrable Leucine-rich repeat kinase 2 (LRRK2) inhibitor with a Ki of 0.7 nM. Mutations in LRRK2 are associated with Parkinson's disease. GNE-0877 inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson’s disease mutation with an IC₅₀ value of 3 nM.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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