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Digallic acid

CAT: 0804-HY-116694Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116694Size:1 Each
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Description
Digallic acid is an antioxidant, antimutagenic, antigenotoxic, and anti-hyperuricemic compound. Digallic acid is a reverse transcriptase and XOD, URAT1 (IC50: 5.34 μM) inhibitor. Digallic acid scavenges DPPH· and O2·− radicals. Digallic acid induces apoptosis. Digallic acid can be isolated from the fruits of Pistascia lentiscus[1][2][3].
CAS Number
536-08-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Reactive Oxygen Species (ROS) ; Reverse Transcriptase; URAT1; Xanthine Oxidase
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Infection; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/digallic-acid.html
Smiles
OC(C1=CC(OC(C2=CC(O)=C(C(O)=C2)O)=O)=C(C(O)=C1)O)=O
Molecular Formula
C14H10O9
Molecular Weight
322.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Bhouri W, et al. Digallic acid from Pistascia lentiscus fruits induces apoptosis and enhances antioxidant activities. Phytother Res. 2012 Mar;26 (3) :387-91. |[2]Nakane H, et al. Differential inhibition of reverse transcriptase and various DNA polymerases by digallic acid and its derivatives. J Nat Prod. 1990 Sep-Oct;53 (5) :1234-40. |[3]Zheng F, et al. Discovery of digallic acid as XOD/URAT1 dual target inhibitor for the treatment of hyperuricemia. Bioorg Chem. 2024 Jun;147:107381.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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