2-Thiothymidine

2-Thiothymidine

• CAS Number: 28585-51-5
• UNSPSC Description: 2-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-thiothymidine.html
• Purity: 99.75
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=S)O[C@@H]1CO
• Molecular Weight: 258.29
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported