PIP-C-3-Azaspiro[5.5]undecane-boc
CAT:
804-HY-161656
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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PIP-C-3-Azaspiro[5.5]undecane-boc
- CAS Number: 3027978-51-1
- UNSPSC Description: PIP-C-3-Azaspiro[5.5]undecane-boc is the linker for PROTAC. PIP-C-3-Azaspiro[5.5]undecane-boc is utilized for synthesis of PROTAC SOS1 degrader-10 (HY-161654)[1].
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pip-c-3-azaspiro-5-5-undecane-boc.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(OC(C)(C)C)N1CCC(CC2)(CC1)CCC2CN3CCNCC3
- Molecular Weight: 351.53
- References & Citations: [1]Wang, K, et al. “Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor.” Bioorganic & medicinal chemistry letters vol. 107 (2024): 129780.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported