2-Methoxyphenyl dihydrouracil-azaspiro[5.5]undecane-C-PIP

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804-HY-161657

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UNSPSC Description: 2-Methoxyphenyl dihydrouracil-azaspiro[5.5]undecane-C-PIP is an E3 Ligase ligand-linker conjugate, and can be used for synthesis of PROTAC SOS1 degrader-10 (HY-161654)[1].
Target Antigen: E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/2-methoxyphenyl-dihydrouracil-azaspiro-5-5-undecane-c-pip.html
Smiles: O=C(N1CCC(CC2)(CC1)CCC2CN3CCNCC3)C4=CC=C(OC)C(N5CCC(NC5=O)=O)=C4
Molecular Weight: 497.63
References & Citations: [1]Wang K, et al. Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor. Bioorg Med Chem Lett. 2024 Jul 15;107:129780.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-161657	2-Methoxyphenyl dihydrouracil-azaspiro[5.5]undecane-C-PIP
HY-161656	PIP-C-3-Azaspiro[5.5]undecane-boc
HY-107755-02	3-Azaspiro[5.5]undecane (hydrochloride)
HY-107755-05	3-Azaspiro[5.5]undecane (hydrochloride)
HY-107755-04	3-Azaspiro[5.5]undecane (hydrochloride)
HY-107755-01	3-Azaspiro[5.5]undecane (hydrochloride)
HY-107755-03	3-Azaspiro[5.5]undecane (hydrochloride)
HY-159598	3-Azaspiro[5.5]undecane-9-methanol
HY-W249500	2-Methoxyphenyl dihydrouracil
HY-W056267-02	3-Boc-3-azaspiro[5.5]undecane-9-carbaldehyde

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