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BAY1217389

CAT: 0804-HY-12859-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12859-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
CAS Number
1554458-53-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Mps1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BAY1217389.html
Purity
99.94
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1CC1)C2=CC=C(C3=CN=C4C(NCCC(F)(F)F)=CC(OC5=CC=C(OC)C(F)=C5F)=NN43)C=C2C
Molecular Formula
C27H24F5N5O3
Molecular Weight
561.50
Precautions
H302, H315, H319, H335
References & Citations
[1]Wengner AM, et al. Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity. Mol Cancer Ther. 2016 Apr;15 (4) :583-92.|[2]Wengner AM, et al. Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity. Mol Cancer Ther. 2016 Apr;15 (4) :583-92.. . . .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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MBS3846022-01BAY1217389
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