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Amidase

CAT: 0804-HY-P2736-01Size: 250 UDry Ice: NoHazardous: No
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CAT#:0804-HY-P2736-01Size:250 U
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes[1].
CAS Number
9012-56-0
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/amidase.html
Solubility
10 mM in DMSO
Smiles
[Amidase]
References & Citations
[1]Weber BW, et al. The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning. J Biol Chem. 2013 Oct 4;288 (40) :28514-23.|[2]Li W, et al. An Amidase Contributes to Full Virulence of Sclerotinia sclerotiorum. Int J Mol Sci. 2022 Sep 23;23 (19) :11207.|[3]Weber BW, et.al. The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning. J Biol Chem. 2013 Oct 4;288 (40) :28514-23.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported

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