Phthalic acid

CAT: 0804-HY-I0508-01Size: 1 gDry Ice: NoHazardous: No
CAT#:0804-HY-I0508-01Size:1 g
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Description
Phthalic acid is the final common metabolite of phthalic acid esters (PAEs) . Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA) . Phthalic acid has applications in the preparation of phthalate ester plasticizers. Phthalic acid exhibits mutagenic effect and causes genetic damage in mammalian germ cells[1][2][3].
CAS Number
[88-99-3]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents; Estrogen Receptor/ERR; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/phthalic-acid.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C1=CC=CC=C1C(O)=O)=O
Molecular Formula
C8H6O4
Molecular Weight
166.13
Precautions
H315, H319, H335
References & Citations
[1]Du Yeon Bang, et al.Toxicological Characterization of Phthalic Acid. Toxicol Res 2011;27:191−203|[2]Jha AM, et al., Germ cell mutagenicity of phthalic acid in mice. Mutat Res. 1998 Dec 3;422 (2) :207-12.|[3]Pavan B, et al., Phthalic acid mimics 17beta-estradiol actions in WISH cells. Toxicol Lett. 2001 Jan 3;118 (3) :157-64.|[4]Bai R, et al., Phthalic acid induces oxidative stress and alters the activity of some antioxidant enzymes in roots of Malus prunifolia. J Chem Ecol. 2009 Apr;35 (4) :488-94.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported

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