Phthalic acid

• Description:

  Phthalic acid is the final common metabolite of phthalic acid esters (PAEs) . Phthalic acid can be used for the synthesis of synthetic agents, such as isophthalic acid (IPA), and terephthalic acid (TPA) . Phthalic acid has applications in the preparation of phthalate ester plasticizers. Phthalic acid exhibits mutagenic effect and causes genetic damage in mammalian germ cells[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  Biochemical Assay Reagents; Estrogen Receptor/ERR; Reactive Oxygen Species (ROS)

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/phthalic-acid.html

• Concentration:

  10mM

• Purity:

  99.99

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OC(C1=CC=CC=C1C(O)=O)=O

• Molecular Formula:

  C8H6O4

• Molecular Weight:

  166.13

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Du Yeon Bang, et al.Toxicological Characterization of Phthalic Acid. Toxicol Res 2011;27:191−203|[2]Jha AM, et al., Germ cell mutagenicity of phthalic acid in mice. Mutat Res. 1998 Dec 3;422 (2) :207-12.|[3]Pavan B, et al., Phthalic acid mimics 17beta-estradiol actions in WISH cells. Toxicol Lett. 2001 Jan 3;118 (3) :157-64.|[4]Bai R, et al., Phthalic acid induces oxidative stress and alters the activity of some antioxidant enzymes in roots of Malus prunifolia. J Chem Ecol. 2009 Apr;35 (4) :488-94.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [88-99-3]