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µ-Conotoxin BuIIIB

CAT: 0804-HY-P5862Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-P5862Size:Inquire
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CAS Number
1400096-06-1
UNSPSC Description
μ-Conotoxin BuIIIB (Mu-Conotoxin BuIIIB) is a mammalian neuronal voltage-gated sodium channel (VGSC) blocker. μ-Conotoxin BuIIIB can be obtained from the venom of Cone snails and is a probe for ion channel function research. μ-Conotoxin BuIIIB can be used in the study of neurological diseases such as pain[1].
Target Antigen
Sodium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)C(C)C)NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H]1CC2=CNC3=CC=CC=C23)=O)CCCNC(N)=N)=O)=O)CSSC[C@H](NC4=O)C(N)=O)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)CC(N)=O)=O)CCCCN)=O)CSSC[C@@H]4NC5=O)=O)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]5CCCNC(N)=N)=O)CO)=O)CC6=CNC=N6)=O)CC(O)=O)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O
Molecular Weight
2763.18
References & Citations
[1]Kuang Z, et al. Mammalian neuronal sodium channel blocker μ-conotoxin BuIIIB has a structured N-terminus that influences potency. ACS Chem Biol. 2013;8(6):1344-51.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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