Exatecan-d5 (mesylate)

Exatecan-d5 (mesylate)

• CAS Number: 2819276-88-3
• UNSPSC Description: Exatecan-d5 (mesylate) is deuterium labeled Exatecan mesylate. Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 0.975 μg/mL[1].
• Target Antigen: ADC Cytotoxin; Topoisomerase
• Type: Isotope-Labeled Compounds
• Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
• Field of Research: Cancer
• Smiles: O=S(C)(O)=O.O=C1[C@](O)(C(C([2H])([2H])[2H])([2H])[2H])C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O
• Molecular Weight: 536.58
• References & Citations: [1]Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.
• Shipping Conditions: Room Temperature