Propiverine-d7 (hydrochloride)

Propiverine-d7 (hydrochloride)

• Product Name Alternative: MSC2363318A
• UNSPSC Description: Propiverine-d7 (hydrochloride) is the deuterium labeled Propiverine hydrochloride. Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence[1][2].
• Target Antigen: Calcium Channel; Isotope-Labeled Compounds; mAChR
• Type: Isotope-Labeled Compounds
• Related Pathways: GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling;Others
• Field of Research: Neurological Disease
• Solubility: 10 mM in DMSO
• Smiles: O=C(C(C1=CC=CC=C1)(C2=CC=CC=C2)OC([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])OC3CCN(CC3)C.Cl
• Molecular Weight: 410.99
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Kitta T, et, al. Effects of propiverine hydrochloride, an anticholinergic agent, on urethral continence mechanisms and plasma catecholamine concentration in rats. Int Urogynecol J. 2013 Apr; 24(4): 683-8.|[3]Ito Y, et, al. Muscarinic Receptor Binding and Plasma Drug Concentration after the Oral Administration of Propiverine in Mice. Low Urin Tract Symptoms. 2010 Apr; 2(1):43-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported