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Propiverine

CAT: 0804-HY-116408Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116408Size:1 Each
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Description
Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2].
CAS Number
60569-19-9
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/propiverine.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C1=CC=CC=C1)(C2=CC=CC=C2)OCCC)OC3CCN(CC3)C
Molecular Formula
C23H29NO3
Molecular Weight
367.48
References & Citations
[1]McKeage K. Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms. Clin Drug Investig. 2013 Jan;33 (1) :71-91.|[2]Madersbacher H, Mürtz G. Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic) . World J Urol. 2001 Nov;19 (5) :324-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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