7-Methyl-guanosine-5'-triphosphate (sodium)

7-Methyl-guanosine-5'-triphosphate (sodium)

• UNSPSC Description: 7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Biochemical Assay Reagents
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/7-methyl-guanosine-5-triphosphate-sodium.html
• Purity: 99.69
• Solubility: H2O : 250 mg/mL (ultrasonic)
• Smiles: OP(OP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)N=C3[O-])=C3[N+](C)=C2)O1)(O)=O)(O)=O)(O)=O.[Na].[x]
• References & Citations: [1]Kowalska J, et al. Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1921-5.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported