7-Methyl-guanosine-5'-triphosphate (sodium)

• UNSPSC Description:

  7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/7-methyl-guanosine-5-triphosphate-sodium.html

• Purity:

  99.69

• Solubility:

  H2O : 250 mg/mL (ultrasonic)

• Smiles:

  OP(OP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)N=C3[O-])=C3[N+](C)=C2)O1)(O)=O)(O)=O)(O)=O.[Na].[x]

• References & Citations:

  [1]Kowalska J, et al. Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1921-5.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported