Mca-SEVKMDAEFRK(Dnp)RR-NH2

Mca-SEVKMDAEFRK(Dnp)RR-NH2

• CAS Number: 1802078-33-6
• UNSPSC Description: Mca-SEVKMDAEFRK(Dnp)RR-NH2, containing the wild-type amyloid precursor protein (APP) beta-secretase cleavage site, is the substrate of thimet oligopeptidase (TOP). It is used for Alzheimer's disease research[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/mca-sevkmdaefrk-dnp-rr-nh2.html
• Solubility: 10 mM in DMSO
• Smiles: N=C(NCCC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CC(C1=CC=C(C=C1O2)OC)=CC2=O)=O)CO)=O)CCC(O)=O)=O)C(C)C)=O)CCCCN)=O)CCSC)=O)CC(O)=O)=O)C)=O)CCC(O)=O)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CCCCNC4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)=O)CCCNC(N)=N)=O)C(N)=O)N
• Molecular Weight: 2033.18
• References & Citations: [1]H Koike, et al. Thimet Oligopeptidase Cleaves the Full-Length Alzheimer Amyloid Precursor Protein at a β-Secretase Cleavage Site in COS Cells. J Biochem. 1999 Jul;126(1):235-42.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported