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SGC activator 2

CAT: 0804-HY-168341Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168341Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SGC activator 2 (Compound 16a) is an activator for soluble guanylate cyclase (sGC), that promotes the cGMP production and exhibits vascular protective and anti-inflammatory activities[1].
UNSPSC
12352005
Target
Guanylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sgc-activator-2.html
Smiles
O=C(OC)N(C1=C(N)N=C(C2=NN(CC3=CC=CC=C3F)C4=C2C=CN(C)C4=O)N=C1N)C
Molecular Formula
C21H21FN8O3
Molecular Weight
452.44
References & Citations
[1]Kintos DP, et al., Identification of new multi-substituted 1H-pyrazolo[3,4-c]pyridin-7 (6H) -ones as soluble guanylyl cyclase (sGC) stimulators with vasoprotective and anti-inflammatory activities. Bioorg Chem. 2024 Mar;144:107170.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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