Sitafloxacin (hydrate)

• UNSPSC Description:

  Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections[1][2][3][4].

• Target Antigen:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Sitafloxacin-hydrate.html

• Purity:

  99.37

• Solubility:

  DMSO : 8.9 mg/mL (ultrasonic;warming)|H2O : < 0.1 mg/mL

• Smiles:

  N[C@H]1C2(CC2)CN(C(C(Cl)=C3N([C@H]4[C@@H](F)C4)C=C(C(O)=O)C5=O)=C(C=C35)F)C1.[1.5 H2O]

• Molecular Weight:

  436.84

• References & Citations:

  [1]Anderson, D.L., Sitafloxacin hydrate for bacterial infections. Drugs Today (Barc), 2008. 44(7): p. 489-501.|[2]Surapee Tiengrim, et al. Comparative in vitro activity of sitafloxacin against bacteria isolated from Thai patients with urinary tract infections and lower respiratory tract infections. J Med Assoc Thai. 2012 Feb;95 Suppl 2:S6-17.|[3]Keating, et al. Sitafloxacin: in bacterial infections. Drugs, 2011. 71(6): p. 731-44.bioRxiv. 2024 Nov 06.|Antimicrob Resist Infect Control. 2019 Feb 15;8:40. |Curr Microbiol. 2021 Dec 14;79(1):12.|Infect Drug Resist. 2019 Jan 31;12:345-358.|PLoS One. 2019 Mar 27;14(3):e0213868.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  Launched

• CAS Number:

  163253-35-8