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Sitafloxacin

CAT: 0804-HY-B0395-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0395-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection[1][2].
CAS Number
127254-12-0
Product Name Alternative
DU6859a
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sitafloxacin.html
Purity
99.37
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN([C@H]2[C@@H](F)C2)C3=C(C=C(F)C(N(C[C@H]4N)CC54CC5)=C3Cl)C1=O)O
Molecular Formula
C19H18ClF2N3O3
Molecular Weight
409.81
Precautions
H302, H315, H319, H335
References & Citations
[1]Okumura R, et al. Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topoisomerase IV: contribution to reducing in vitro emergence of quinolone-resistant Streptococcus pneumoniae. J Antimicrob Chemother. 2008 Jul;62 (1) :98-104.|[2]Dhople AM, et al. Activities of sitafloxacin (DU-6859a), either singly or in combination with rifampin, against Mycobacterium ulcerans infection in mice. J Chemother. 2003 Feb;15 (1) :47-52.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Quinolone
Citation 01
Antimicrob Resist Infect Control. 2019 Feb 15:8:40.|Curr Microbiol. 2021 Dec 14;79 (1) :12.|Infect Drug Resist. 2019 Jan 31:12:345-358.|PLoS One. 2019 Mar 27;14 (3) :e0213868.|bioRxiv. 2024 Nov 06.

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B3322-5Sitafloxacin
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MBS5817213Sitafloxacin monohydrate
A10847-100Sitafloxacin 100mg
A10847-50Sitafloxacin 50mg
T75286-01Sitafloxacin hydrochloride

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