β-Aminopropionitrile
CAT:
804-HY-Y1750-01
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
β-Aminopropionitrile
- CAS Number: 151-18-8
- UNSPSC Description: β-Aminopropionitrile (BAPN) is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes[1][2].
- Target Antigen: Endogenous Metabolite; Monoamine Oxidase
- Type: Natural Products
- Related Pathways: Metabolic Enzyme/Protease;Neuronal Signaling
- Applications: Cancer-programmed cell death
- Field of Research: Cancer; Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/β-aminopropionitrile.html
- Purity: 99.99
- Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
- Smiles: N#CCCN
- Molecular Weight: 70.09
- References & Citations: [1]Miana M, et al. The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats. Dis Model Mech. 2015 Jun;8(6):543-51.|[2]Yang X, et al. Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. Oncol Rep. 2013 Feb;29(2):541-8.|[3]Ren W, et al. β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice. Sci Rep. 2016 Jun 22;6:28149.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported