HLA-DRa antibody

CAT: 0013-GTR18398450-01Size: 0.1 mLDry Ice: NoHazardous: No

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CAT#:0013-GTR18398450-01Size:0.1 mL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

HLA-DRa antibody validated for immunohistochemistry on 76 different Normal Tissues

Product Name Alternative

DR alpha chain; DRB1; DRB4; HLA class II histocompatibility antigen DR alpha chain; HLA DR1B; HLA DR3B; HLA DRA; HLA-DRA; HLADR4B; HLADRA1; HLADRB; Major histocompatibility complex class II DR alpha; Major histocompatibility complex class II DR beta 1/3/4/5

UniProt

P01903

Reactivity

Human

Clonality

Monoclonal

Clone

MSVA-470R

Conjugation

Unconjugated

Field of Research

Cell Biology

Dilution

1:100-1:200

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Positive Control: Liver: An at least moderate staining should be seen of sinusoids and Kupffer cells. Kidney: An at least moderate staining should be seen in small capillaries of glomeruli. Negative Control: Absence of HLA-DRa staining is expected in hepatocytes of a completely normal liver and in tubuli of completely normal kidney. Cellular Localization: Cell Surface Protocol Recommendations: Manual Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining) . Heat-induced antigen retrieval for 5 minutes in an autoclave at 121°C in pH 7.8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:150 at 37°C for 60 minutes. Visualization of bound antibody by the EnVision Kit (Dako, Agilent) according to the manufacturer’s directions.

Tested Applications

IHC

Host or Source

Rabbit

Isotype

IgG

UniProtKB · P01903

HLA class II histocompatibility antigen, DR alpha chain

DRA_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P01903
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: HLA-DRA
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: A2BET4, Q30160, Q6IAZ1, Q861I2, Q9TP70

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Adaptive immunityHost-virus interactionImmunity

Cellular component

Cell membraneCytoplasmic vesicleEndoplasmic reticulumEndosomeLysosomeMembraneMHC II

PTM

Disulfide bondGlycoproteinIsopeptide bondUbl conjugation

Domain

SignalTransmembraneTransmembrane helix

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