Aftin-4

• Description :

  Aftin-4 is an Amyloid-β42 (Aβ42) inducer.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Amyloid-β

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Aftin-4.html

• Purity :

  98.44

• Solubility :

  DMSO : ≥ 100 mg/mL

• Smiles :

  CC[C@@H](NC1=NC(N(C)CC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1)CO

• Molecular Formula :

  C20H28N6O

• Molecular Weight :

  368.48

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Meunier J, et al. Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative. J Alzheimers Dis. 2015;44 (2) :507-24.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [866893-90-5]