Aftin-4

• UNSPSC Description:

  Aftin-4 is an Amyloid-β42 (Aβ42) inducer.

• Target Antigen:

  Amyloid-β

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Aftin-4.html

• Purity:

  98.44

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  CC[C@@H](NC1=NC(N(C)CC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1)CO

• Molecular Weight:

  368.48

• References & Citations:

  [1]Meunier J, et al. Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative. J Alzheimers Dis. 2015;44(2):507-24.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  866893-90-5