EGFR kinase inhibitor 6

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

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804-HY-162483

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EGFR kinase inhibitor 6

UNSPSC Description: EGFR kinase inhibitor 6 (Compound 4b) is an orally active inhibitor for epidermal growth factor receptor (EGFR) kinase, with IC50 of 24.34 μM. EGFR kinase inhibitor 6 induces apoptosis. EGFR kinase inhibitor 6 exhibits anticancer and anti-inflammatory activity with low toxicity (LD50 range: 500-2000 mg/kg)[1].
Target Antigen: Apoptosis; EGFR
Type: Reference compound
Related Pathways: Apoptosis;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications: COVID-19-immunoregulation
Field of Research: Cancer; Inflammation/Immunology
Assay Protocol: https://www.medchemexpress.com/egfr-kinase-inhibitor-6.html
Solubility: 10 mM in DMSO
Smiles: O=C1C(C)SC(C2=C(C3=CC=CC=C3)N=C4N2C=CS4)N1C5=CC=C(Cl)C=C5
Molecular Weight: 425.95
References & Citations: [1]Kamboj P, et al., Design, synthesis, biological assessment and molecular modeling studies of novel imidazothiazole-thiazolidinone hybrids as potential anticancer and anti-inflammatory agents. Sci Rep. 2024 Apr 11;14(1):8457.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Complementary Product Range

Our range of products, including EGFR kinase inhibitor 6, falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

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Cat	Name
HY-162482	EGFR kinase inhibitor 5
HY-157166	EGFR kinase inhibitor 2
HY-162299-01	EGFR kinase inhibitor 3
HY-162483	EGFR kinase inhibitor 6
HY-162300	EGFR kinase inhibitor 4
HY-159512	EGFR kinase inhibitor 7
HY-162299-04	EGFR kinase inhibitor 3
HY-162299-03	EGFR kinase inhibitor 3
HY-162299-02	EGFR kinase inhibitor 3
HY-143246	EGFR kinase inhibitor 1