DPPC-13C2

CAT: 0804-HY-109506S9Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-109506S9Size:1 mg
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Description
DPPC-13C2 is a deuterated labeled DPPC[1]. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice[2][3][4][5][6].
CAS Number
[65277-91-0]
Product Name Alternative
129Y83-13C2
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds; Liposome
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dppc-13c2.html
Purity
95.0
Smiles
CCCCCCCCCCCCCCC[13C](O[C@H](CO[13C](CCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Molecular Formula
C38 13C2H80NO8P
Molecular Weight
736.02
References & Citations
[1]Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10 (6) :781-811.|[2]Akiko Uemura, et al. Induction of immune responses against glycosphingolipid antigens: comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci. 2005 Dec;67 (12) :1197-201.|[3]Ege C, et al. Insertion of Alzheimer's A beta 40 peptide into lipid monolayers. Biophys J. 2004 Sep;87 (3) :1732-40.|[4]Kalra VK, et al. Transport of amino acids in gamma-glutamyl transpeptidase-implanted human erythrocytes. J Biol Chem. 1981 Jun 10;256 (11) :5567-71.|[5]Leekumjorn S, et al. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers. Biophys J. 2006 Jun 1;90 (11) :3951-65.|[6]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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