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ALA-A2 peptide

CAT: 0804-HY-P10711Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10711Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ALA-A2 is an anticancer peptide discovered in alpha-lactalbumin that selectively kills cancer cells by inducing Autophagy. ALA-A2 has cell-penetrating capabilities, allowing it to effectively enter cells without relying on membranolytic effects. In A549 lung cancer cells, ALA-A2 demonstrates significant dose-dependent anticancer activity. ALA-A2 holds promise for research in cancer therapy and autophagy regulation[1].
UNSPSC
12352209
Target
Autophagy
Type
Peptides
Related Pathways
Autophagy
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ala-a2-peptide.html
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CS)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N
Molecular Formula
C67H111N21O19S
Molecular Weight
1546.79
References & Citations
[1]Lerksuthirat T, et al. ALA-A2 Is a Novel Anticancer Peptide Inspired by Alpha-Lactalbumin: A Discovery from a Computational Peptide Library, In Silico Anticancer Peptide Screening and In Vitro Experimental Validation. Glob Chall. 2023 Jan 12;7 (3) :2200213.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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