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Rat IL-1β Protein

CAT: 0749-PRP1219-01Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0749-PRP1219-01Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-1β (IL-1β or IL-1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. IL-1β is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by Interleukin 1β in the central nervous system (CNS) . IL-1β gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Description
Rat IL-1β protein, expressed in E. coli
Product Name Alternative
IL-1; IL-1 beta; IL-1B; IL1-BETA; IL1F2; Interleukin-1 beta; IL1B
Gene ID
24494
Accession Number
Q63264
Tag
IL-1β
Type
Cytokines and proteins
Applications
No tag
Purity
> 98 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Weight
17.4 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized Rat IL-1β proteinshould be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Protein Length
The recombinant Rat IL-1β consists of 152 amino acids and has a predicted molecular mass of 17.4 KDa.
Formulation
Lyophilized from sterile 20mM Tris with 150 mM NaCl, , pH 7.4.
Applications Notes
Rat
Other Product Names
IL-1; IL-1 beta; IL-1B; IL1-BETA; IL1F2; Interleukin-1 beta; IL1B
Recommended Usage
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Rat IL-1 beta protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Preparation
E. coli
Accession Number URL
https://www.uniprot.org/uniprot/Q63264
AA Sequence
Amino acid sequence derived from Rat IL-1β (Q63264) (Val117-Ser268) was expressed.

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