CCL20 (human, recombinant)

• Short Description:

  Catalog Number: B2017260 (50 µg)_x000D_ CCL20 (human, recombinant) is a lab-produced version of the human chemokine ligand 20 protein. It recruits immune cells like lymphocytes and dendritic cells to inflammation sites by binding to the CCR6 receptor. Produced using recombinant DNA technology, it is used in research on immune response, inflammation, and cancer. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Description:

  CCL20 (human, recombinant)_x000D_ Catalog number: B2017260_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 10.2 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: ˆ’80°C_x000D_ Keywords: β-chemokine Exodus-1, Liver and Activation-regulated Chemokine, Macrophage Inflammatory Protein 3-α, MIP-3-α, Small-inducible Cytokine A20_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Wang D, Yang L, Yu W, Wu Q, Lian J, Li F, Liu S, Li A, He Z, Liu J, Sun Z, Yuan W, Zhang Y. Colorectal cancer cell-derived CCL20 recruits regulatory T cells to promote chemoresistance via FOXO1/CEBPB/NF-κB signaling J Immunother Cancer. 2019 Aug 8;7(1):215._x000D_ 2: Wei Y, Lao XM, Xiao X, Wang XY, Wu ZJ, Zeng QH, Wu CY, Wu RQ, Chen ZX, Zheng L, Li B, Kuang DM. Plasma Cell Polarization to the Immunoglobulin G Phenotype in Hepatocellular Carcinomas Involves Epigenetic Alterations and Promotes Hepatoma Progression in Mice Gastroenterology. 2019 May;156(6):1890-1904.e16._x000D_ 3: Matti C, D'Uonnolo G, Artinger M, Melgrati S, Salnikov A, Thelen S, Purvanov V, Strobel TD, Spannagel L, Thelen M, Legler DF. CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4 J Leukoc Biol. 2020 Jun;107(6):1137-1154._x000D_ 4: Graf KT, Liu H, Filler SG, Bruno VM. Depletion of Extracellular Chemokines by Aspergillus Melanin mBio. 2023 Jun 27;14(3):e0019423._x000D_ 5: Alaaeddine N, Hilal G, Baddoura R, Antoniou J, Di Battista JA. CCL20 stimulates proinflammatory mediator synthesis in human fibroblast-like synoviocytes through a MAP kinase-dependent process with transcriptional and posttranscriptional control J Rheumatol. 2011 Sep;38(9):1858-65._x000D_ 6: Hosokawa Y, Shindo S, Hosokawa I, Ozaki K, Matsuo T. IL-6 trans-signaling enhances CCL20 production from IL-1β-stimulated human periodontal ligament cells Inflammation. 2014 Apr;37(2):381-6._x000D_ 7: Lee HJ, Choi SC, Choi EY, Lee MH, Seo GS, Kim EC, Yang BJ, Lee MS, Shin YI, Park KI, Jun CD. Iron chelator induces MIP-alpha/CCL20 in human intestinal epithelial cells: implication for triggering mucosal adaptive immunity Exp Mol Med. 2005 Aug 31;37(4):297-310._x000D_ 8: Ghosh M, Shen Z, Schaefer TM, Fahey JV, Gupta P, Wira CR. CCL20/MIP3alpha is a novel anti-HIV-1 molecule of the human female reproductive tract Am J Reprod Immunol. 2009 Jul;62(1):60-71._x000D_ 9: Bandow K, Smith A, Watkins T, Shenk S, Gerami-Naini B, Garlick JA. CC chemokine ligand 20 (CCL20) positively regulates collagen type I production in 3D skin equivalent tissues Exp Dermatol. 2023 Apr;32(4):379-391._x000D_ 10: Cook KW, Letley DP, Ingram RJ, Staples E, Skjoldmose H, Atherton JC, Robinson K. CCL20/CCR6-mediated migration of regulatory T cells to the Helicobacter pylori-infected human gastric mucosa Gut. 2014 Oct;63(10):1550-9. _x000D_ _x000D_ Products Related to CCL20 (human, recombinant) can be found at Proteins

• CAS Number:

  9000-83-3

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5