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EGF Polyclonal Antibody

CAT: 0749-ABP0189Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP0189Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EGF encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in EGFare the cause of hypomagnesemia type 4. Dysregulation of EGF has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Description
Rabbit Anti-EGF Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Pro-epidermal growth factor; EGF; Epidermal growth factor; Urogastrone
Gene ID
1950
Accession Number
P01133
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human EGF protein at amino acid sequence of 1000-1060
Clonality
Polyclonal
Tag
EGF
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
130kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of EGF
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:500-200; ELISA 1:10000-20000; IF 1:50-200
Other Product Names
Pro-epidermal growth factor; EGF; Epidermal growth factor; Urogastrone
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P01133
Isotype
Rabbit IgG

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