CCL3 Rabbit Polyclonal Antibody

CCL3 Rabbit Polyclonal Antibody

• Description: Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP)-1α, MIP-1β, MIP-2, MIP-3α, MIP-3β, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. Research has shown that MIP-1β is more selective than MIP-1α, primarily attracting CD4+ T lymphocytes, with a preference for T cells of the naive phenotype. MIP-1α is a more potent lymphocyte chemoattractant than MIP-1β and exhibits a broader range of chemoattractant specificities. It has been suggested that CD8+ T lymphocytes are involved in the control of HIV infection in vivo by the release of HIV-suppressive factors (HIV-SF). MIP-1α has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1β and RANTES
• Product Name Alternative: C C motif chemokine 3 antibody CCL 3 antibody CCL3 antibody CCL3_HUMAN antibody Chemokine C C motif ligand 3 antibody G0/G1 switch regulatory protein 19 1 antibody G0/G1 switch regulatory protein 19-1 antibody G0S19 1 antibody G0S19 1 protein antibody Heparin binding chemotaxis protein antibody L2G25B antibody LD78 alpha antibody LD78-alpha (4-69) antibody LD78alpha antibody Macrophage inflammatory protein 1 alpha antibody Macrophage inflammatory protein 1-alpha antibody MIP 1 alpha antibody MIP 1A antibody MIP-1-alpha antibody MIP-1-alpha (4-69) antibody MIP1A antibody PAT 464.1 antibody SCYA 3 antibody SCYA3 antibody SIS alpha antibody SIS beta antibody SIS-beta antibody Small inducible cytokine A3 antibody small inducible cytokine A3 (homologous to mouse Mip-1a) antibody Small-inducible cytokine A3 antibody Tonsillar lymphocyte LD78 alpha protein antibody
• Abbreviation: MIP-1-alpha
• CAS Number: 9007-83-4
• Swiss Prot: P10147 Human, P10855 Mouse, P50229 Rat
• Cellular Locus: Secreted
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within mouse CCL3 aa 43-92 / 92.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC, ELISA
• Positive Control: HeLa cell lysate, PANC-1 cell lysate, rat brain tissue lysate, mouse brain tissue lysate, mouse lung tissue lysate, Hela, PANC-1, A549, mouse pancreas tissue, mouse lung tissue, mouse spleen tissue, A549 cell lysate.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 10 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No