CCL3 Rabbit Polyclonal Antibody

• Description:

  Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP)-1α, MIP-1β, MIP-2, MIP-3α, MIP-3β, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. Research has shown that MIP-1β is more selective than MIP-1α, primarily attracting CD4+ T lymphocytes, with a preference for T cells of the naive phenotype. MIP-1α is a more potent lymphocyte chemoattractant than MIP-1β and exhibits a broader range of chemoattractant specificities. It has been suggested that CD8+ T lymphocytes are involved in the control of HIV infection in vivo by the release of HIV-suppressive factors (HIV-SF). MIP-1α has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1β and RANTES.

• Product Name Alternative:

  C C motif chemokine 3 antibody CCL 3 antibody CCL3 antibody CCL3_HUMAN antibody Chemokine C C motif ligand 3 antibody G0/G1 switch regulatory protein 19 1 antibody G0/G1 switch regulatory protein 19-1 antibody G0S19 1 antibody G0S19 1 protein antibody Heparin binding chemotaxis protein antibody L2G25B antibody LD78 alpha antibody LD78-alpha (4-69) antibody LD78alpha antibody Macrophage inflammatory protein 1 alpha antibody Macrophage inflammatory protein 1-alpha antibody MIP 1 alpha antibody MIP 1A antibody MIP-1-alpha antibody MIP-1-alpha (4-69) antibody MIP1A antibody PAT 464.1 antibody SCYA 3 antibody SCYA3 antibody SIS alpha antibody SIS beta antibody SIS-beta antibody Small inducible cytokine A3 antibody small inducible cytokine A3 (homologous to mouse Mip-1a) antibody Small-inducible cytokine A3 antibody Tonsillar lymphocyte LD78 alpha protein antibody

• Abbreviation:

  MIP-1-alpha

• Swiss Prot:

  P10855 Mouse

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide within N-terminal mouse CCL3.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  IF-Cell, IHC-P, FC, ELISA

• Positive Control:

  Hela, PANC-1, A549, mouse pancreas tissue, mouse lung tissue, mouse spleen tissue.

• Concentration:

  1 mg/mL

• Dilution:

  IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;ELISA: 1:5,000-1:20,000

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4