Products for Research Use Only
RegisterLogin

Active+Pro Caspase-9 Rabbit Polyclonal Antibody

CAT: 0992-R1308-12Size: 100 µLDry Ice: NoHazardous: No
Product image 1Product image 2
1 / 2
CAT#:0992-R1308-12Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. It is known to be involved in the activation cascade of caspases responsible for apoptosis execution. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Another cleavage occurs at Asp330 producing a p37 subunit that can serve to amplify the apoptotic response. Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to initiate a caspase cascade, which leads to apoptosis.
CAS Number
9007-83-4
Product Name Alternative
Caspase9 APAF-3 antibody APAF3 antibody Apoptosis related cysteine peptidase antibody Apoptotic protease Mch-6 antibody Apoptotic protease-activating factor 3 antibody CASP-9 antibody CASP9 antibody CASP9_HUMAN antibody Caspase 9 apoptosis related cysteine peptidase antibody Caspase 9 Dominant Negative antibody Caspase 9c antibody Caspase-9 antibody Caspase-9 subunit p10 antibody ICE LAP6 antibody ICE like apoptotic protease 6 antibody ICE-LAP6 antibody ICE-like apoptotic protease 6 antibody MCH6 antibody PPP1R56 antibody protein phosphatase 1, regulatory subunit 56 antibody RNCASP9 antibody
Abbreviation
CASP-9,APAF-3,ICE-LAP6
Swiss Prot
P55211 Human
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human Caspase-9 aa 299-313/416.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
HeLa cell lysate, HeLa treated with 1μM staurosporine for 4 hours cell lysate, HeLa treated with 3μM staurosporine for 4 hours cell lysate, human lung carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000- 1:2,000 ;IHC-P: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 46 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Related Products

CatalogName
HA750238Active+Pro Caspase-9 Recombinant Rabbit monoclonal Antibody
ET1608-64active+pro Caspase-3 Recombinant Rabbit Monoclonal Antibody [SU38-04]
ET1701-22pro Caspase-9 Recombinant Rabbit Monoclonal Antibody [JJ08-05]
HA750048Pro Caspase-3 Recombinant Rabbit monoclonal Antibody
HA750062Caspase-9 Recombinant Rabbit monoclonal Antibody
HA750159Cleaved+pro Caspase-3 Recombinant Rabbit monoclonal Antibody
ET1603-26pro Caspase-3 Recombinant Rabbit Monoclonal Antibody [SZ02-08]
HA723907Human Caspase-9 Recombinant Rabbit monoclonal Antibody
HA723906Human Caspase-9 Recombinant Rabbit monoclonal Antibody
ET1612-28pro Caspase-7 Recombinant Rabbit Monoclonal Antibody [SD20-57]

Alternative Products

CatalogName
53246-01Caspase-9 Rabbit Polyclonal Antibody
NB100-56118SSRabbit Polyclonal Caspase-9 Antibody
GTR18095405Caspase 9 Rabbit Polyclonal Antibody

Popular Products