WDR77 Recombinant Rabbit Monoclonal Antibody [PSH0-07]

• Description:

  Methylosome protein 50 is a protein that in humans is encoded by the WDR77 gene. Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

• Product Name Alternative:

  2610312E17Rik antibody Androgen receptor cofactor p44 antibody C79984 antibody HKMT1069 antibody MEP 50 antibody MEP-50 antibody MEP50 antibody MEP50_HUMAN antibody Methylosome protein 50 antibody MGC2722 antibody Nbla10071 antibody p44 antibody p44/Mep50 antibody RGD1310479 antibody RP11 552M11.3 antibody WD repeat containing protein 77 antibody WD repeat domain 77 antibody WD repeat-containing protein 77 antibody WDR77 antibody

• Abbreviation:

  WDR77

• Swiss Prot:

  Q9BQA1 Human

• Cellular Locus:

  Nucleus, Cytoplasm.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Recombinant protein within human WDR77 aa 1-342 / 342.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IHC-P, FC

• Positive Control:

  Human prostate tissue, human fallopian tube tissue, mouse brain tissue, HepG2 cell lysate, 293 cell lysate, K562 cell lysate, Hela, HepG2.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000 ;IHC-P: 1:1,000 ;FC: 1:500-1:1,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 37 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3