ACE2 Recombinant Rabbit Monoclonal Antibody [SN0754]

• Description:

  Angiotensin-converting enzyme (ACE) is a carboxyl-terminal dipeptidyl exopeptidase that converts angiotensin I to the potent vasopressive hormone, angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in blood pressure regulation and fluid/electrolyte homeostasis. ACE2 is the first known human homolog of ACE. Unlike ACE, which is expressed ubiquitously throughout the vasculature, ACE2 is expressed only in cardiac, renal and testicular cells.

• Product Name Alternative:

  ACE 2 antibody ACE related carboxypeptidase antibody ACE-related carboxypeptidase antibody ACE2 antibody ACE2_HUMAN antibody ACEH antibody Angiotensin converting enzyme 2 antibody Angiotensin converting enzyme homolog antibody Angiotensin converting enzyme like protein antibody Angiotensin I Converting Enzyme (peptidyl dipeptidase A) 2 antibody Angiotensin I converting enzyme 2 antibody Angiotensin-converting enzyme homolog antibody DKFZP434A014 antibody EC 3.4.17 antibody metalloprotease MPROT 15 antibody Metalloprotease MPROT15 antibody OTTHUMP00000022963 antibody Processed angiotensin-converting enzyme 2 antibody

• Abbreviation:

  ACEH, ACE2

• Swiss Prot:

  Q9BYF1 Human, Q8R0I0 Mouse, Q5EGZ1 Rat, A0A1U7QTA1 Hamster

• Cellular Locus:

  Cell membrane, Cell projection, Cytoplasm, Membrane, Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat, Hamster

• Immunogen:

  Synthetic peptide within Human ACE2 aa 181-230 / 805.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, IF-Tissue, IP

• Positive Control:

  HepG2 cell lysate, 293T cell lysate, rat brain tissue lysate, rat kidney tissue lysate, human kidney tissue lysate, human small intestine tissue lysate, mouse kidney tissue lysate, mouse testis tissue lysate, hamster testis lysates, hamster stomach tissue lysates, 293, MCF-7, HepG2, human kidney tissue, human testis tissue, mouse kidney tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000-1:5,000 ;IF-Cell: 1:100-1:500 ;IHC-P: 1:1,000 ;IF-Tissue: 1:200 ;IP: Use at an assay dependent concentration.

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 92 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3