NAPSIN A Recombinant Rabbit Monoclonal Antibody [PD01-30]

NAPSIN A Recombinant Rabbit Monoclonal Antibody [PD01-30]

• Description: This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. Napsin A plays a role in pneumocyte surfactant processing. In normal tissue, Anti-Napsin A specifically labels type II pneumocytes in adult lung and epithelial cells in kidney tissues. In abnormal tissues, Napsin A is strongly positive in over 80% of primary lung adenocarcinomas and 79% of renal cell carcinoma by immunohistochemistry. Napsin A is a useful marker for lung adenocarcinoma. The combined use of Napsin A and thyroid transcription factor-1 (TTF-1) improves the sensitivity and specificity for identification of pulmonary adenocarcinoma.
• Product Name Alternative: Asp 4 antibody ASP4 antibody Aspartyl protease 4 antibody KAP antibody Kdap antibody Kidney derived aspartic protease like protein antibody NAP1 antibody NAPA antibody Napsa antibody NAPSA_HUMAN antibody Napsin 1 antibody napsin A aspartic peptidase antibody Napsin A precursor antibody Napsin-1 antibody Napsin-A antibody Pronapsin A antibody SNAPA antibody TA01/TA02 antibody
• Abbreviation: Napsin-A Aspartyl protease 4 (ASP4; Asp 4) Napsin-1 TA01/TA02 NAPSA NAP1 NAPA
• CAS Number: 9000-83-3
• Swiss Prot: O96009 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant fragment within Human NAPSIN A aa 1-150.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: IHC-P
• Positive Control: Human lung carcinoma tissue, human kidney tissue.
• Concentration: 1 mg/mL
• Dilution: IHC-P: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 45 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes