HLA DMB Recombinant Rabbit Monoclonal Antibody [JE58-74]

HLA DMB Recombinant Rabbit Monoclonal Antibody [JE58-74]

• Description: HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
• Product Name Alternative: class II antigen HLA-DM beta chain antibody class II histocompatibility antigen antibody Class II histocompatibility antigen M beta chain antibody D6S221E antibody DMB antibody HLA class II histocompatibility antigen DM beta chain antibody HLA-DM histocompatibility type, beta chain antibody M beta chain antibody Major histocompatibility complex class II DM beta antibody MHC class II antigen DMB antibody MHC class II antigen HLA DM beta chain antibody MHC class II HLA DMB antibody OTTHUMP00000029257 antibody Really interesting new gene 7 protein antibody RING 7 antibody RING7 antibody
• Abbreviation: HLA-DMB
• CAS Number: 9000-83-3
• Swiss Prot: P28068 Human
• Cellular Locus: Late endosome membrane, Lysosome membrane.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within human HLA DMB aa 1-100/263.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, FC
• Positive Control: Raji cell lysate, Daudi cell lysate, PANC-1, Daudi.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;FC: 1:500-1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 29 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes