TCP1 delta Mouse Monoclonal Antibody [A8E2]

TCP1 delta Mouse Monoclonal Antibody [A8E2]

• Description: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable). The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin, as well as alpha-transducin (MIM 139330).
• Product Name Alternative: CCT delta antibody CCT4 antibody CCTD antibody chaperonin containing t-complex polypeptide 1, delta subunit antibody chaperonin containing TCP1, subunit 4 (delta) antibody SRB antibody Stimulator of TAR RNA binding antibody T complex protein 1 subunit delta antibody TCP-1-delta antibody
• Abbreviation: T-complex protein 1 subunit delta TCP-1-delta CCT-delta Stimulator of TAR RNA-binding CCT4 CCTD SRB
• CAS Number: 9007-83-4
• Swiss Prot: P50991 Human, P80315 Mouse, Q7TPB1 Rat
• Cellular Locus: Cytoskeleton
• Host: Mouse
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within human TCP1 delta aa 200-450.
• Isotype: IgG1
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell
• Positive Control: Hela cell lysate, A549 cell lysate, PC-12 cell lysate, SH-SY5Y cell lysate, THP-1 cell lysate, PC-3M cell lysate, Jurkat cell lysate, mouse testis tissue lysate, rat spleen tissue lysate, rat brain tissue lysate, human breast carcinoma tissue, human stomach tissue.
• Concentration: 1.1 mg/mL
• Dilution: WB: 1:1,000;IHC-P: 1:800
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 58 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No